Lecturer Email: tuoilt@hnue.edu.vn TRAINING PROCESS 2008 BSc. – HNUE, Vietnam  2010 MSc. – HNUE, Vietnam 2016 PhD. – SunMoon University, Korea 2016 - 2017 Postdoctoral Researcher – SunMoon University, Korea 2017 Lecturer – HNUE, Vietnam

RESEARCH INTERESTS

1. Cordyceps militaris strains generation by ascospore hybridization.

2. Enzymatic modification of plant natural products.

SELECTED PUBLICATIONS

1. Le, TT., Pandey, RP., Gurung, RB., Dhakal, D., Sohng, JK. 2014. Efficient enzymatic systems for synthesis of novel α mangostin glycosides exhibiting antibacterial activity against Gram-positive bacteria. Applied microbiology and biotechnology 98 (20), 8527-8538.

2. Dhakal, D., Le, TT., Pandey, RP., Jha, AK., Gurung, RB., Parajuli, P., Pokhrel, AR., Yoo, JC., Sohng, JK. 2015. Enhanced Production of Nargenicin A1 and Generation of Novel Glycosylated Derivatives. Applied biochemistry and biotechnology, 1-16.

3. Pandey, RP., Gurung, RB., Parajuli, P., Koirala, N., Le, TT., Sohng, JK. Assessing acceptor substrate promiscuity of YjiC-mediated glycosylation toward flavonoids. 2014. Carbohydrate research 393, 26-31.

4. Pokhrel, AR., Chaudhary, AK., Nguyen, HT., Dhakal, D., Le, TT., Shrestha, A., Liou, K., Sohng, JK. Overexpression of a pathway specific negative regulator enhances production of daunorubicin in bldA deficient Streptomyces peucetius ATCC 27952. 2016. Microbiol Res 192, 96-102.

5. Gurung RB, Gong SY, Dhakal D, Le TT, Jung NR, Jung HJ, Oh TJ, Sohng JK. Synthesis of Curcumin Glycosides with Enhanced Anticancer Properties Using One-Pot Multienzyme Glycosylation Technique. 2017. J Microbiol Biotechnol 27(9),1639-1648.

6. Tae-Su Kim, Tuoi Thi Le, Hue Thi Nguyen, Kye Woon Cho, Jae Kyung Sohng. Mutational analyses for product specificity of YjiC towards α-mangostin mono-glucoside. Enzyme and Microbial Technology, 2018 (118), 76-82.

7. KW Cho, TS Kim, TT Le, HT Nguyen, YS Oh, RP Pandey, JK Sohng. Altering UDP-glucose Donor Substrate Specificity of Bacillus licheniformis Glycosyltransferase towards TDP-glucose. J. Microbiol. Biotechnol, 2019, 29(2), 268–273.

8. SM Kim, JM Han, TT Le, JK Sohng, HJ Jung. Anticancer and antiangiogenic activties of novel a-mangostin glycosides in human hepatocellular carcinoma cells via downregulation of c-Met and HIF-1α. Int J Mol Sci, 2020, 21(11):4043. doi: 10.3390/ijm21114043.

9. Le Thi Tuoi, Le Thi Hue, Cao Tuan Kiet, Nguyen Duc Hieu, Do Thi Hong, Le Thi Tuyet Mai, Vu Thi Bich Huyen. Effect of coordination nutritional ingredients on the development and cordycepin, adenosin production of Cordyceps militaris. HNUE Journal of Science, Natural Science, 2021, 66(4F): 82-91. (in Vietnamease).